Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
LOC100697436Solute carrier family 8 member 4a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (945 aa)    
Predicted Functional Partners:
LOC100699977
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 
  0.867
prkaca
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.
   
 
  0.615
LOC100700452
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
   
 
  0.615
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 
  0.615
slc8a3
Solute carrier family 8 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
     
  0.613
I3KKU4_ORENI
Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab.
      
 0.527
LOC100709284
Solute carrier family 8 member 1a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
     
  0.494
Slc8a1
Solute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
     
  0.494
akap1
A kinase (PRKA) anchor protein 1b.
     
  0.486
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
      
 0.428
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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