GNG4 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

GNG4

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4. (75 aa)

Predicted Functional Partners:

LOC100702054

0.971

pik3r5

0.962

LOC100711075

0.944

drd2

0.938

drd3

0.938

oprd1

0.938

LOC100712332

0.938

LOC100697329

0.938

LOC100706781

0.936

LOC100690007

0.936

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNG4	LOC100690007	ENSONIP00000002212	ENSONIP00000010381	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Phosphoinositide-3-kinase regulatory subunit 5.	0.936
GNG4	LOC100697329	ENSONIP00000002212	ENSONIP00000080047	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family.	0.938
GNG4	LOC100702054	ENSONIP00000002212	ENSONIP00000003304	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide binding protein (G protein), beta 5b.	0.971
GNG4	LOC100706781	ENSONIP00000002212	ENSONIP00000002013	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.	0.936
GNG4	LOC100711075	ENSONIP00000002212	ENSONIP00000013592	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.944
GNG4	LOC100712332	ENSONIP00000002212	ENSONIP00000056535	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Opioid receptor, mu 1; Belongs to the G-protein coupled receptor 1 family.	0.938
GNG4	drd2	ENSONIP00000002212	ENSONIP00000007762	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family.	0.938
GNG4	drd3	ENSONIP00000002212	ENSONIP00000017685	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.938
GNG4	oprd1	ENSONIP00000002212	ENSONIP00000040488	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Opioid receptor, delta 1b; Belongs to the G-protein coupled receptor 1 family.	0.938
GNG4	pik3r5	ENSONIP00000002212	ENSONIP00000022874	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Phosphoinositide-3-kinase, regulatory subunit 5.	0.962
LOC100690007	GNG4	ENSONIP00000010381	ENSONIP00000002212	Phosphoinositide-3-kinase regulatory subunit 5.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	0.936
LOC100690007	LOC100702054	ENSONIP00000010381	ENSONIP00000003304	Phosphoinositide-3-kinase regulatory subunit 5.	Guanine nucleotide binding protein (G protein), beta 5b.	0.923
LOC100690007	LOC100706781	ENSONIP00000010381	ENSONIP00000002013	Phosphoinositide-3-kinase regulatory subunit 5.	Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.	0.980
LOC100690007	LOC100711075	ENSONIP00000010381	ENSONIP00000013592	Phosphoinositide-3-kinase regulatory subunit 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.932
LOC100690007	pik3r5	ENSONIP00000010381	ENSONIP00000022874	Phosphoinositide-3-kinase regulatory subunit 5.	Phosphoinositide-3-kinase, regulatory subunit 5.	0.960
LOC100697329	GNG4	ENSONIP00000080047	ENSONIP00000002212	Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	0.938
LOC100697329	LOC100702054	ENSONIP00000080047	ENSONIP00000003304	Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide binding protein (G protein), beta 5b.	0.945
LOC100697329	LOC100711075	ENSONIP00000080047	ENSONIP00000013592	Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.920
LOC100697329	LOC100712332	ENSONIP00000080047	ENSONIP00000056535	Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family.	Opioid receptor, mu 1; Belongs to the G-protein coupled receptor 1 family.	0.916
LOC100697329	oprd1	ENSONIP00000080047	ENSONIP00000040488	Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family.	Opioid receptor, delta 1b; Belongs to the G-protein coupled receptor 1 family.	0.916