Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100708570Barrier-to-autointegration factor-like protein. (90 aa)    
Predicted Functional Partners:
lemd3
LEM domain containing 3.
    
 0.845
Vrk2
VRK serine/threonine kinase 2; Belongs to the protein kinase superfamily.
    
 0.805
I3JYI3_ORENI
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
    
 0.805
LOC100711486
Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma.
    
 0.782
ankle2
Ankyrin repeat and LEM domain containing 2.
    
 0.779
lmnb2
Lamin B2; Belongs to the intermediate filament family.
    
 0.723
gins1
GINS complex subunit 1 (Psf1 homolog).
      
 0.715
LOC100702944
Uncharacterized protein.
    
 0.714
LOC100692045
RNA binding motif protein 39b.
    
 0.714
I3K885_ORENI
Uncharacterized protein; Belongs to the intermediate filament family.
    
 0.709
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (24%) [HD]