Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sema3bSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (806 aa)    
Predicted Functional Partners:
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 0.973
LOC100690065
Plexin C1.
    
 0.671
cdk5
Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.
     
 0.655
I3KBB2_ORENI
Plexin A3.
    
 0.644
PLXND1
Plexin D1.
    
 0.644
PLXNA2
Plexin A2.
    
 0.644
LOC100710907
Plexin A2.
    
 0.644
plxna1
Plexin A1.
    
 0.644
plxna4
Plexin A4.
    
 0.644
ENSONIP00000070314
Plexin A3 isoform X1.
    
 0.644
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.