Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100702158Ceramide synthase 4a. (413 aa)    
Predicted Functional Partners:
acer3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
    
 0.961
SGPP2
Sphingosine-1-phosphate phosphatase 2.
    
 0.959
LOC100698562
Phosphatidic acid phosphatase type 2D.
    
 0.941
LOC100711669
Si:ch211-212g7.6.
   
 0.939
Kdsr
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.939
ugcg
UDP-glucose ceramide glucosyltransferase.
   
 
 0.939
Sgpp1
acidPPc domain-containing protein.
   
 0.939
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.937
asah2
Neutral ceramidase.
     
 0.937
degs1
Delta(4)-desaturase, sphingolipid 1.
   
 0.935
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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