Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100707752Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (592 aa)    
Predicted Functional Partners:
cth
Cystathionase (cystathionine gamma-lyase), like.
 0.999
mtr
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.974
ahcy
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
  
 0.959
Selenbp1
Selenium binding protein 1.
     
 0.946
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.945
LOC100693502
AdoHcyase_NAD domain-containing protein; Belongs to the adenosylhomocysteinase family.
  
 0.944
LOC100695211
Zgc:172121; Involved in the regulation of homocysteine metabolism.
  
 
 0.943
psph
Phosphoserine phosphatase.
    
 0.942
LOC100704302
Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism.
  
 
 0.940
I3JKS7_ORENI
PALP domain-containing protein.
  
 
 0.936
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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