Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sgk2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (364 aa)    
Predicted Functional Partners:
pdpk1
3-phosphoinositide dependent protein kinase 1b.
    
 0.983
foxo4
Forkhead box O4.
    
 0.963
foxo3
Forkhead box O3b.
    
 0.963
LOC100706939
Forkhead box O1 a.
    
 0.963
LOC100706370
Fork-head domain-containing protein.
    
 0.963
LOC100699299
Fork-head domain-containing protein.
    
 0.960
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.942
LOC100696396
Forkhead box O6 b.
    
 0.931
LOC100701297
Forkhead box O6 a.
    
 0.928
Sgk3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.907
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]