STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3J0S2_ORENIKinase suppressor of ras 1a. (900 aa)    
Predicted Functional Partners:
LOC100708547
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
 0.778
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
0.778
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
 0.778
LOC100697571
Mitogen-activated protein kinase kinase 2b.
   
 0.778
ppp5c
Serine/threonine-protein phosphatase.
   
 0.751
I3JW49_ORENI
A-Raf proto-oncogene, serine/threonine kinase.
    
0.706
braf
B-Raf proto-oncogene serine/threonine-protein kinase.
    
0.706
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
0.706
cnksr1
Connector enhancer of kinase suppressor of ras 1 isoform X1.
    
 0.633
LOC100700668
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family.
   
 0.629
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.