STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100711821Anti-silencing function 1Ba histone chaperone. (197 aa)    
Predicted Functional Partners:
LOC100695474
Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.
    
 0.970
chaf1b
Chromatin assembly factor 1, subunit B.
   
 
 0.929
mcm2
DNA helicase; Belongs to the MCM family.
   
 
 0.928
I3JYD6_ORENI
Calcineurin binding protein 1.
    
 0.894
ENSONIP00000030784
Ubinuclein 1.
    
 0.894
Chek2
Checkpoint kinase 2.
   
 
 0.867
nasp
Nuclear autoantigenic sperm protein (histone-binding).
   
 
 0.867
NASP
Nuclear autoantigenic sperm protein.
   
 
 0.867
hat1
Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.
   
 
 0.866
I3KTN8_ORENI
Tankyrase_bdg_C domain-containing protein.
    
 0.819
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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