Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fam126aFamily with sequence similarity 126 member A. (503 aa)    
Predicted Functional Partners:
ttc7b
Tetratricopeptide repeat domain 7B.
    
 
 0.965
ttc7a
Tetratricopeptide repeat domain 7A.
    
 
 0.869
pi4ka
Phosphatidylinositol 4-kinase, catalytic, alpha b; Belongs to the PI3/PI4-kinase family.
    
 
 0.809
I3JZ86_ORENI
Phosphatidylinositol 4-kinase, catalytic, alpha a; Belongs to the PI3/PI4-kinase family.
    
 
 0.809
shpk
Sedoheptulokinase.
    
   0.768
LYPD6
LY6/PLAUR domain containing 6.
      
 0.707
LOC100700867
Transmembrane protein 109.
      
 0.695
mapkapk2
MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily.
      
 0.680
efr3a
EFR3 homolog A (S. cerevisiae).
      
 0.679
I3IY44_ORENI
WD repeat domain 92.
    
 
 0.676
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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