Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Ubr4Ubiquitin protein ligase E3 component n-recognin 4. (5106 aa)    
Predicted Functional Partners:
LOC100710260
Uncharacterized protein.
    
 
 0.941
kcmf1
Potassium channel modulatory factor 1.
    
 
 0.941
Vegfd
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
   0.855
huwe1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
 
 0.851
Abhd10
Transgelin 3b.
    
   0.771
ubxn7
UBX domain protein 7.
   
   0.765
sars2
Seryl-tRNA synthetase 2, mitochondrial.
    
   0.759
exosc3
Exosome component 3.
      
 0.755
Ubr2
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.733
ubxn1
UBX domain protein 1.
    
   0.717
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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