Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HES2Hes family bHLH transcription factor 2, tandem duplicate 1. (267 aa)    
Predicted Functional Partners:
fancf
FA complementation group F.
    
  0.775
fancg
FA complementation group G.
    
  0.775
fancc
FA complementation group C.
    
  0.775
fancl
FA complementation group L.
    
  0.775
LOC100707106
Recombination signal binding protein for immunoglobulin kappa J region-like.
    
 0.733
LOC106098755
Recombination signal binding protein for immunoglobulin kappa J region a.
    
 0.733
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.733
LOC100705644
Hes family bHLH transcription factor 6.
    
 0.635
LOC100692400
Hairy-related 13.
    
 0.635
rpl10a
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
  0.616
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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