Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Nek11Protein kinase domain-containing protein. (432 aa)    
Predicted Functional Partners:
CDC25B
Cell division cycle 25B.
   
 0.788
rpgrip1l
RPGRIP1 like.
   
 
 0.723
LOC100708748
RPGR interacting protein 1.
    
 
 0.638
cmc2
COX assembly mitochondrial protein 2 homolog.
      
 0.629
ttc21b
Tetratricopeptide repeat domain 21B.
    
 
 0.629
snrnp35
Small nuclear ribonucleoprotein 35 (U11/U12).
      
 0.601
chek1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
 0.588
cep162
Centrosomal protein 162.
    
   0.581
ENSONIP00000076950
Spermatogenesis associated 7.
   
 
 0.549
Rpgr
Uncharacterized protein.
    
 0.534
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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