Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100696175Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (266 aa)    
Predicted Functional Partners:
LOC100708633
Carboxypeptidase A1 (pancreatic).
   
 
 0.745
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
   
  
 0.693
LOC100710041
Ribonucleotide reductase M2 b.
     
 0.551
LOC100710506
Uncharacterized protein.
      
 0.536
lasp1
LIM and SH3 protein 1.
      
 0.536
Amn
Amnion associated transmembrane protein.
     
 0.508
LOC100705573
PX domain-containing protein.
      
 0.489
LOC100704253
Transmembrane and immunoglobulin domain containing 1.
      
 0.489
I3KRC2_ORENI
Uncharacterized protein.
     
 0.479
RRM2
Ribonucleotide reductase regulatory subunit M2.
     
 0.479
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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