Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100697412Tyrosine-protein kinase. (583 aa)    
Predicted Functional Partners:
sh2d1a
SH2 domain containing 1A duplicate b.
   
 0.869
cd247
T-cell surface glycoprotein CD3 zeta chain.
   
 0.798
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.780
cdc42
Cell division cycle 42.
   
 0.773
ptprc
Protein tyrosine phosphatase receptor type C.
   
 0.770
Bcar1
BCAR1 scaffold protein, Cas family member.
    
 0.769
Nedd9
Neural precursor cell expressed, developmentally down-regulated 9.
    
 0.769
pag1
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.747
ptpra
Receptor-type tyrosine-protein phosphatase alpha.
   
 0.740
cd3e
T-cell surface glycoprotein CD3 epsilon chain.
   
 0.736
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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