Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100534578Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)    
Predicted Functional Partners:
I3K566_ORENI
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.999
tnfaip3
Tumor necrosis factor, alpha-induced protein 3.
   
 0.995
tradd
Tnfrsf1a-associated via death domain.
    
 0.994
LOC100707066
Interleukin-1.
   
 0.991
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.991
tab1
TGF-beta activated kinase 1/MAP3K7 binding protein 1.
    
 0.989
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.988
sharpin
RanBP2-type domain-containing protein.
    
 0.986
optn
Optineurin.
    
 0.982
il10
Interleukin 10.
   
 
 0.980
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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