Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100707647NADPH oxidase organizer 1a. (528 aa)    
Predicted Functional Partners:
LOC100705310
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
    
 0.882
I3KWG4_ORENI
NADPH oxidase activator 1.
   
 0.878
LOC100711071
Neutrophil cytosolic factor 2.
   
 0.835
nox4
NADPH oxidase 4.
   
 0.799
nox1
NADPH oxidase 1.
   
 0.757
I3KPB6_ORENI
NADPH oxidase, EF-hand calcium binding domain 5.
   
 0.720
LOC100705711
Cytochrome b-245, beta polypeptide (chronic granulomatous disease).
   
 0.701
xkrx
XK-related protein.
   
 0.673
xk
XK-related protein.
   
 0.673
ncf4
Neutrophil cytosolic factor 4.
     
 0.666
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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