Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC100710139Si:ch211-221f10.2. (1392 aa)    
Predicted Functional Partners:
gopc
Golgi-associated PDZ and coiled-coil motif containing.
    
 0.545
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.531
LOC100712516
ATP-binding cassette, sub-family C (CFTR/MRP), member 3.
     
 0.524
LOC100704025
ATP-binding cassette, sub-family C (CFTR/MRP), member 1.
     
 0.524
LOC100691027
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a.
     
 0.524
suox
Sulfite oxidase.
   
 
 0.516
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
  0.516
LOC100693338
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
  
 0.468
LOC102081483
Ubiquitin-conjugating enzyme E2 variant 1.
     
  0.454
rapgef4
Rap guanine nucleotide exchange factor (GEF) 4.
    
 0.446
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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