Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100693591Cartilage intermediate layer protein 2. (1247 aa)    
Predicted Functional Partners:
mtbp
MDM2 binding protein.
      
 0.617
I3KMU3_ORENI
Insulin-like growth factor 1.
   
 
 0.559
ENSONIP00000033282
Fat storage-inducing transmembrane protein 1.
      
 0.544
LOC100711327
Fat storage inducing transmembrane protein 1, like.
      
 0.544
mef2b
Myocyte enhancer factor 2b.
      
 0.522
LOC100708038
Ras-related protein Rab-6B.
      
 0.522
cep19
Centrosomal protein 19.
      
 0.492
vwa5b2
Von Willebrand factor A domain containing 5B2.
      
 0.492
scly
Selenocysteine lyase.
      
 0.491
rfxank
Regulatory factor X-associated ankyrin-containing protein.
    
 
 0.483
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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