Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100703527Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (363 aa)    
Predicted Functional Partners:
drd2
Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family.
    
 0.950
drd3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
    
 0.950
LOC100711263
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
  0.947
LOC100702089
Apelin receptor b; Belongs to the G-protein coupled receptor 1 family.
    
 0.947
LOC100712161
Opioid receptor, kappa 1; Belongs to the G-protein coupled receptor 1 family.
    
  0.947
lpar1
Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.947
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.946
LOC100692921
Purinergic receptor P2Y12.
    
  0.944
LOC102079696
Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.
    
 0.941
LOC100704531
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.941
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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