Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISL2ISL LIM homeobox 2b. (364 aa)    
Predicted Functional Partners:
lhx4
LIM homeobox 4.
   
 0.807
LHX3
LIM homeobox 3.
   
 0.807
I3IYF2_ORENI
LIM domain binding 2a.
    
 0.807
I3JSU9_ORENI
LIM domain binding 1a.
    
 0.807
LOC100706951
LIM-domain binding 1b.
    
 0.807
nkx2-5
NK2 homeobox 5.
    
 0.749
tbx20
T-box transcription factor 20.
   
 0.738
znf511
Zinc finger protein 511.
    
   0.650
gata4
GATA binding protein 4.
    
 0.620
idi1
Isopentenyl-diphosphate delta isomerase 1.
    
   0.593
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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