Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100700785Proline-serine-threonine phosphatase interacting protein 1b. (420 aa)    
Predicted Functional Partners:
ENSONIP00000000682
Intersectin 2a.
   
 0.939
I3KKD0_ORENI
Intersectin 2b.
   
 0.939
LOC100700076
Proline-serine-threonine phosphatase interacting protein 1a.
     
  0.916
itsn1
Intersectin 1 (SH3 domain protein).
   
 0.869
LOC100705827
Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.
    
 
 0.777
ptpn12
Uncharacterized protein.
   
 
 0.727
LOC100705060
Protein tyrosine phosphatase non-receptor type 18.
   
 
 0.727
LOC100710113
Protein tyrosine phosphatase non-receptor type 22.
   
 
 0.727
LOC100711937
WASP like actin nucleation promoting factor a.
   
 0.718
I3K140_ORENI
WASP like actin nucleation promoting factor b.
   
 0.718
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.