Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
upf3bUPF3B regulator of nonsense mediated mRNA decay. (464 aa)    
Predicted Functional Partners:
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
 0.998
smg5
SMG5 nonsense mediated mRNA decay factor.
   
 0.991
LOC100693655
Uncharacterized protein.
    
 0.990
UPF1
UPF1 RNA helicase and ATPase.
    
 0.990
smg6
SMG6 nonsense mediated mRNA decay factor.
   
 0.982
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
   
 0.965
casc3
Casc3 exon junction complex subunit.
    
 0.961
magoh
Mago homolog, exon junction complex subunit.
    
 0.961
rbm8a
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.961
srrm1
Serine/arginine repetitive matrix 1.
    
 0.946
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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