Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tdp2Tyrosyl-DNA phosphodiesterase 2b. (362 aa)    
Predicted Functional Partners:
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
   0.548
rps27a
Ribosomal protein S27a.
    
   0.548
sumo1
Small ubiquitin-related modifier.
   
 
 0.521
tdp1
Tyrosyl-DNA phosphodiesterase 1.
   
  
 0.454
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6.
     
 0.453
ENSONIP00000047919
Ubiquitin B.
    
   0.425
acot13
Acyl-CoA thioesterase 13.
      
 0.411
znf451
Zinc finger protein 451.
      
 0.410
pola2
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
      
 0.409
aasdh
Aminoadipate-semialdehyde dehydrogenase.
      
 0.407
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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