Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sash3SAM and SH3 domain containing 3. (398 aa)    
Predicted Functional Partners:
LOC102077683
CAP-ZIP_m domain-containing protein.
   
  
 0.621
RNF207
Ring finger protein 207.
      
 0.616
ptprc
Protein tyrosine phosphatase receptor type C.
   
 
 0.541
I3KPE6_ORENI
Sorting nexin 20.
   
  
 0.515
arhgap25
Rho GTPase activating protein 25.
   
  
 0.499
LOC100693073
T cell activation RhoGTPase activating protein.
   
  
 0.498
I3KMS3_ORENI
Uncharacterized protein.
      
 0.495
rogdi
Rogdi atypical leucine zipper.
      
 0.479
LOC102077259
FYN-binding protein 1 isoform X1.
   
  
 0.463
themis2
Thymocyte selection associated family member 2.
   
  
 0.459
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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