Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tpd52Tumor protein D52. (249 aa)    
Predicted Functional Partners:
I3KC69_ORENI
Tpd52 like 2b.
   
   0.966
mal2
Mal, T cell differentiation protein 2 (gene/pseudogene).
   
 
 0.879
LOC100691058
Tpd52 like 2a.
   
   0.779
mrps2
Mitochondrial ribosomal protein S2.
    
   0.757
Ppp1r26
Protein phosphatase 1 regulatory subunit 26.
    
   0.757
gak
Cyclin G associated kinase.
     
 0.613
pllp
Plasmolipin.
    
 
 0.586
snx8
Sorting nexin 8a.
     
 0.567
LOC100691194
Vesicle-associated membrane protein 8.
     
 0.563
grin3b
Glutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb.
    
   0.559
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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