STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nox1NADPH oxidase 1. (572 aa)    
Predicted Functional Partners:
LOC100705310
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.830
ncf1
Neutrophil cytosolic factor 1.
   
 0.816
LOC100711071
Neutrophil cytosolic factor 2.
   
 0.796
I3KWG4_ORENI
NADPH oxidase activator 1.
   
 0.786
nox4
NADPH oxidase 4.
  
 
0.699
duoxa2
Dual oxidase 2.
   
 
 0.668
ncf4
Neutrophil cytosolic factor 4.
   
 0.663
LOC100704359
Uncharacterized protein.
     
 0.641
LOC100707647
NADPH oxidase organizer 1a.
   
 0.617
LOC100705987
NADPH oxidase organizer 1b.
   
 0.617
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.