Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC100709239Par-6 family cell polarity regulator gamma b. (452 aa)    
Predicted Functional Partners:
cdc42
Cell division cycle 42.
    
 0.987
LOC100703104
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.980
prkci
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.980
Mpp5
Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.
   
 0.957
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
   
 0.957
LOC100703449
Par-6 family cell polarity regulator alpha.
   
  0.947
PARD3
Par-3 family cell polarity regulator.
   
 0.922
LOC100698856
Par-3 family cell polarity regulator alpha, b.
   
 0.922
pard6b
Par-6 partitioning defective 6 homolog beta (C. elegans).
     
  0.916
I3K2K5_ORENI
Uncharacterized protein.
   
 0.813
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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