Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
negr1Neuronal growth regulator 1. (359 aa)    
Predicted Functional Partners:
iglon5
IgLON family member 5.
   
 
 0.587
ksr2
Kinase suppressor of ras 2.
  
 
 0.581
Fgfr2
Fibroblast growth factor receptor.
   
 0.517
SLITRK1
SLIT and NTRK like family member 1.
   
 0.511
serpine2
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.
     
 0.453
RELN
Reelin.
      
 0.452
s1pr1
Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.441
efnb2
Ephrin-B2a; Belongs to the ephrin family.
    
 
 0.435
TMEM236
Transmembrane protein 236.
      
 0.431
LOC100707859
Transmembrane protein 236.
      
 0.431
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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