Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100705111Immunoglobulin superfamily, DCC subclass, member 4. (1233 aa)    
Predicted Functional Partners:
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.911
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.911
unc5b
Unc-5 netrin receptor B.
    
 0.839
NTN1
Netrin 1.
    
 0.829
LOC100703122
Netrin 5.
    
 0.829
LOC100698643
Netrin 2.
    
 0.829
LOC100711643
Netrin 1b.
    
 0.829
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.800
I3J1I3_ORENI
Hemojuvelin BMP co-receptor.
    
 0.776
I3JB83_ORENI
RGM domain family, member D.
    
 0.776
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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