STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arhgef6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (771 aa)    
Predicted Functional Partners:
PAK3
P21 (RAC1) activated kinase 3.
    
 0.980
PAK2
Non-specific serine/threonine protein kinase.
    
 0.975
pak2
Non-specific serine/threonine protein kinase.
    
 0.975
pak5
Non-specific serine/threonine protein kinase.
    
 0.962
LOC100708294
Non-specific serine/threonine protein kinase.
    
 0.961
pak6
Non-specific serine/threonine protein kinase.
    
 0.961
LOC100696183
Non-specific serine/threonine protein kinase.
    
 0.961
RAC2
Rac family small GTPase 2.
   
 0.955
LOC100696401
Ras-related C3 botulinum toxin substrate 1-like.
   
 0.955
RAC1
Rac family small GTPase 1.
   
 0.955
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.