Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
myocMyocilin. (482 aa)    
Predicted Functional Partners:
wdr36
WD repeat domain 36.
      
 0.679
optn
Optineurin.
      
 0.547
cyp1b1
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
      
 0.511
LOC100690118
Myosin, light chain 2b, regulatory, cardiac, slow.
    
 
 0.506
MYL2
Myosin light chain 2.
    
 
 0.506
ENSONIP00000066554
annotation not available
   
  
 0.488
rb1
Retinoblastoma 1.
      
 0.456
ENSONIP00000064579
Reprimo, TP53-dependent G2 arrest mediator candidate.
      
 0.444
Marveld1
MARVEL domain-containing protein 1.
      
 0.443
telo2
TEL2, telomere maintenance 2, homolog (S. cerevisiae).
      
 0.443
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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