Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100710697Uncharacterized protein. (329 aa)    
Predicted Functional Partners:
LOC100710431
Paraoxonase 2.
   
  0.966
I3J275_ORENI
Nuclear transcription factor Y, gamma.
    
   0.904
lcat
Lecithin-cholesterol acyltransferase.
   
  
 0.680
cetp
Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
      
 0.673
LOC100699941
Putative apolipoprotein E.
   
  
 0.662
LOC100705942
Microseminoprotein, beta-like.
   
  
 0.635
LOC100694673
Microsomal glutathione S-transferase 1.2.
   
  
 0.595
I3KZC6_ORENI
Apolipoprotein F.
   
  
 0.557
LOC100711490
Uncharacterized protein.
   
  
 0.499
apoa4b
Putative apolipoprotein A4b.
   
  
 0.499
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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