Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aktipAkt interacting protein. (296 aa)    
Predicted Functional Partners:
hook2
Hook microtubule-tethering protein 2.
   
 
 0.955
tnfsf13b
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
 
 0.950
HOOK3
Hook microtubule tethering protein 3.
   
 
 0.939
I3J3C3_ORENI
Hook microtubule-tethering protein 1.
   
 
 0.939
fam160a2
Family with sequence similarity 160 member A2.
    
 
 0.914
fam160a1
Family with sequence similarity 160 member A1a.
    
 
 0.873
LOC100693653
Uncharacterized protein.
    
 
 0.873
LOC100695394
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
   0.761
rbm33
RNA binding motif protein 33a.
   
  
 0.676
ube2g2
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
      
 0.618
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (10%) [HD]