Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100700190Cysteine-rich hydrophobic domain 1. (264 aa)    
Predicted Functional Partners:
LOC100699888
STIP1 homology and U-Box containing protein 1.
    
 
 0.771
dlg3
Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family.
      
 0.698
dab2
DAB adaptor protein 2.
      
 0.685
prlr
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.
      
 0.649
STUB1
STIP1 homology and U-box containing protein 1.
    
 
 0.597
pdgfra
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
      
 0.592
LOC100706148
FIP1 like 1b (S. cerevisiae).
      
 0.575
wasf3
WASP family member 3b.
      
 0.570
rlim
Ring finger protein, LIM domain interacting.
      
 0.537
scarb1
Scavenger receptor class B, member 1; Belongs to the CD36 family.
      
 0.536
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.