STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (669 aa)    
Predicted Functional Partners:
lrp2
Low density lipoprotein receptor-related protein 2a.
    
 0.854
vldlr
Very low density lipoprotein receptor.
    
 0.840
I3JQH3_ORENI
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.
    
 0.815
ldlr
Low density lipoprotein receptor a.
    
 0.810
LOC100711575
Low-density lipoprotein receptor isoform X2.
    
 0.810
LOC100712136
Uncharacterized protein.
    
 0.810
LOC100707208
Golgi phosphoprotein 3.
    
 
 0.716
golph3
Golgi phosphoprotein 3.
    
 
 0.716
LOC100690003
Low density lipoprotein receptor-related protein 2b.
    
 0.709
egf
Epidermal growth factor.
    
 0.681
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.