Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC1006916713-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)    
Predicted Functional Partners:
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.973
LOC100706096
Aldedh domain-containing protein.
   
 0.937
ALDH6A1
Aldehyde dehydrogenase 6 family member A1.
   
 0.937
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 
 0.922
LOC100711605
Malate synthase-like.
  
 
 0.921
abat
4-aminobutyrate aminotransferase.
     
 0.903
acox1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
   
 0.903
pccb
Propionyl-CoA carboxylase subunit beta.
   
 0.903
LOC100703463
Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family.
   
 0.901
LOC100707441
Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family.
   
 0.901
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.