Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kdrKinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)    
Predicted Functional Partners:
Vegfb
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.957
vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.952
Vegfd
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 0.948
rpl23a
Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
      
 0.941
Vegfa
Vascular endothelial growth factor A isoform X3.
    
 0.911
LOC100711438
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.909
LOC100696779
SHC (Src homology 2 domain containing) transforming protein 2.
   
 0.896
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 0.896
LOC100710015
Uncharacterized protein.
    
 0.891
I3KWA4_ORENI
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.888
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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