Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100706212Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa)    
Predicted Functional Partners:
LOC100709377
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.763
hsd3b7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family.
   
 
 0.754
LOC100534568
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
   
 
 0.754
dhcr7
7-dehydrocholesterol reductase.
     
 0.709
I3K981_ORENI
Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
     
 0.675
sult4a1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
    
  0.665
LOC100706381
Arylsulfatase H.
   
 
 0.650
Sts
Steroid sulfatase (microsomal), isozyme S.
   
 
 0.650
dhcr24
24-dehydrocholesterol reductase.
     
 0.633
I3KSH9_ORENI
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 
  0.633
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.