Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dcun1d4DCN1-like protein. (280 aa)    
Predicted Functional Partners:
cul2
Cullin 2; Belongs to the cullin family.
   
 0.902
cul1
Cullin 1b; Belongs to the cullin family.
   
 0.892
ube2m
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.833
ube2f
Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.833
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.832
LOC109194151
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.832
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
   
 0.815
Fryl
Furry homolog, like.
      
 0.804
Cul4b
Cullin-4B.
    
 0.749
cul4a
Cullin 4A; Belongs to the cullin family.
    
 0.749
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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