Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fezf2FEZ family zinc finger 2. (425 aa)    
Predicted Functional Partners:
wnt1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.819
six3
SIX homeobox 3a.
   
  
 0.681
satb2
DNA-binding protein SATB.
    
 
 0.658
actr8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.596
Tbr1
T-box brain transcription factor 1b.
   
 
 0.591
foxn4
Forkhead box N4.
    
 0.581
cux2
Homeobox protein cut-like.
    
 
 0.570
LOC100698634
Forkhead box N1.
    
 0.547
ENSONIP00000012427
Autoimmune regulator.
   
 0.518
telo2
TEL2, telomere maintenance 2, homolog (S. cerevisiae).
      
 0.514
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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