I3J4X9_ORENI protein (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

I3J4X9_ORENI

Uncharacterized protein. (938 aa)

Predicted Functional Partners:

derl1

0.921

derl2

0.854

LOC100692885

0.854

amfr

0.850

os9

0.850

erlec1

0.850

syvn1

0.850

ube2j1

0.735

spata5l1

0.722

vcp

0.722

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3J4X9_ORENI	LOC100692885	ENSONIP00000003919	ENSONIP00000017529	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.854
I3J4X9_ORENI	amfr	ENSONIP00000003919	ENSONIP00000003079	Uncharacterized protein.	Autocrine motility factor receptor b.	0.850
I3J4X9_ORENI	derl1	ENSONIP00000003919	ENSONIP00000009190	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.921
I3J4X9_ORENI	derl2	ENSONIP00000003919	ENSONIP00000014579	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.854
I3J4X9_ORENI	erlec1	ENSONIP00000003919	ENSONIP00000055307	Uncharacterized protein.	Endoplasmic reticulum lectin 1.	0.850
I3J4X9_ORENI	os9	ENSONIP00000003919	ENSONIP00000024030	Uncharacterized protein.	OS9 endoplasmic reticulum lectin.	0.850
I3J4X9_ORENI	spata5l1	ENSONIP00000003919	ENSONIP00000016753	Uncharacterized protein.	Spermatogenesis associated 5-like 1.	0.722
I3J4X9_ORENI	syvn1	ENSONIP00000003919	ENSONIP00000077660	Uncharacterized protein.	Synovial apoptosis inhibitor 1, synoviolin.	0.850
I3J4X9_ORENI	ube2j1	ENSONIP00000003919	ENSONIP00000002116	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2, J1.	0.735
I3J4X9_ORENI	vcp	ENSONIP00000003919	ENSONIP00000048463	Uncharacterized protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.722
LOC100692885	I3J4X9_ORENI	ENSONIP00000017529	ENSONIP00000003919	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.854
LOC100692885	amfr	ENSONIP00000017529	ENSONIP00000003079	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor b.	0.901
LOC100692885	derl1	ENSONIP00000017529	ENSONIP00000009190	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.995
LOC100692885	derl2	ENSONIP00000017529	ENSONIP00000014579	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.916
LOC100692885	erlec1	ENSONIP00000017529	ENSONIP00000055307	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.902
LOC100692885	os9	ENSONIP00000017529	ENSONIP00000024030	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.915
LOC100692885	spata5l1	ENSONIP00000017529	ENSONIP00000016753	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Spermatogenesis associated 5-like 1.	0.826
LOC100692885	syvn1	ENSONIP00000017529	ENSONIP00000077660	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Synovial apoptosis inhibitor 1, synoviolin.	0.914
LOC100692885	ube2j1	ENSONIP00000017529	ENSONIP00000002116	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2, J1.	0.703
LOC100692885	vcp	ENSONIP00000017529	ENSONIP00000048463	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.929