Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adamts18ADAM metallopeptidase with thrombospondin type 1 motif, 18. (1251 aa)    
Predicted Functional Partners:
sall4
Spalt-like transcription factor 4.
   
  
 0.678
selenos
Selenoprotein S.
      
 0.633
ush1c
USH1 protein network component harmonin.
      
 0.632
ccdc51
Coiled-coil domain containing 51.
      
 0.629
Irx3
Iroquois homeobox 3a.
   
  
 0.623
thsd1
Thrombospondin, type I, domain containing 1.
     
 0.611
FBN1
Fibrillin 1.
    
 0.605
LOC100701533
G protein-coupled receptor 84.
      
 0.575
I3KSE3_ORENI
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.575
sbspon
Somatomedin B and thrombospondin type 1 domain containing.
     
 0.558
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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