RS1 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

RS1

Retinoschisin 1. (255 aa)

Predicted Functional Partners:

dthd1

0.700

rp2

0.610

sp2

0.580

pros1

0.573

sarm1

0.550

prph2

0.545

I3KW89_ORENI

0.545

LOC100698014

0.545

LOC100706449

0.545

fech

0.529

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3KW89_ORENI	RS1	ENSONIP00000029927	ENSONIP00000003966	Peripherin 2-like a.	Retinoschisin 1.	0.545
LOC100698014	RS1	ENSONIP00000035502	ENSONIP00000003966	Uncharacterized protein.	Retinoschisin 1.	0.545
LOC100706449	RS1	ENSONIP00000081480	ENSONIP00000003966	Peripherin 2b (retinal degeneration, slow).	Retinoschisin 1.	0.545
RS1	I3KW89_ORENI	ENSONIP00000003966	ENSONIP00000029927	Retinoschisin 1.	Peripherin 2-like a.	0.545
RS1	LOC100698014	ENSONIP00000003966	ENSONIP00000035502	Retinoschisin 1.	Uncharacterized protein.	0.545
RS1	LOC100706449	ENSONIP00000003966	ENSONIP00000081480	Retinoschisin 1.	Peripherin 2b (retinal degeneration, slow).	0.545
RS1	dthd1	ENSONIP00000003966	ENSONIP00000011643	Retinoschisin 1.	Death domain containing 1.	0.700
RS1	fech	ENSONIP00000003966	ENSONIP00000049512	Retinoschisin 1.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.529
RS1	pros1	ENSONIP00000003966	ENSONIP00000054627	Retinoschisin 1.	Protein S.	0.573
RS1	prph2	ENSONIP00000003966	ENSONIP00000008775	Retinoschisin 1.	Peripherin 2a (retinal degeneration, slow).	0.545
RS1	rp2	ENSONIP00000003966	ENSONIP00000005790	Retinoschisin 1.	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.	0.610
RS1	sarm1	ENSONIP00000003966	ENSONIP00000010294	Retinoschisin 1.	Sterile alpha and TIR motif containing 1.	0.550
RS1	sp2	ENSONIP00000003966	ENSONIP00000000145	Retinoschisin 1.	Sp2 transcription factor.	0.580
dthd1	RS1	ENSONIP00000011643	ENSONIP00000003966	Death domain containing 1.	Retinoschisin 1.	0.700
fech	RS1	ENSONIP00000049512	ENSONIP00000003966	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Retinoschisin 1.	0.529
pros1	RS1	ENSONIP00000054627	ENSONIP00000003966	Protein S.	Retinoschisin 1.	0.573
prph2	RS1	ENSONIP00000008775	ENSONIP00000003966	Peripherin 2a (retinal degeneration, slow).	Retinoschisin 1.	0.545
rp2	RS1	ENSONIP00000005790	ENSONIP00000003966	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.	Retinoschisin 1.	0.610
rp2	sp2	ENSONIP00000005790	ENSONIP00000000145	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.	Sp2 transcription factor.	0.499
sarm1	RS1	ENSONIP00000010294	ENSONIP00000003966	Sterile alpha and TIR motif containing 1.	Retinoschisin 1.	0.550