| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| I3KE17_ORENI | LOC100696013 | ENSONIP00000058778 | ENSONIP00000020011 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | 0.492 |
| I3KE17_ORENI | LOC100704054 | ENSONIP00000058778 | ENSONIP00000060011 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4; Belongs to the cytochrome P450 family. | 0.624 |
| I3KE17_ORENI | LOC100709377 | ENSONIP00000058778 | ENSONIP00000041817 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.603 |
| I3KE17_ORENI | dhcr24 | ENSONIP00000058778 | ENSONIP00000032242 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 24-dehydrocholesterol reductase. | 0.926 |
| I3KE17_ORENI | dhcr7 | ENSONIP00000058778 | ENSONIP00000004013 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 7-dehydrocholesterol reductase. | 0.937 |
| LOC100696013 | I3KE17_ORENI | ENSONIP00000020011 | ENSONIP00000058778 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.492 |
| LOC100696013 | LOC100696185 | ENSONIP00000020011 | ENSONIP00000073431 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | Delta7-sterol 5-desaturase. | 0.835 |
| LOC100696013 | LOC100702293 | ENSONIP00000020011 | ENSONIP00000024904 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 0.648 |
| LOC100696013 | LOC100704054 | ENSONIP00000020011 | ENSONIP00000060011 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4; Belongs to the cytochrome P450 family. | 0.937 |
| LOC100696013 | LOC100709377 | ENSONIP00000020011 | ENSONIP00000041817 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.963 |
| LOC100696013 | Sqle | ENSONIP00000020011 | ENSONIP00000000207 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | Squalene epoxidase a. | 0.879 |
| LOC100696013 | dhcr24 | ENSONIP00000020011 | ENSONIP00000032242 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | 24-dehydrocholesterol reductase. | 0.945 |
| LOC100696013 | dhcr7 | ENSONIP00000020011 | ENSONIP00000004013 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | 7-dehydrocholesterol reductase. | 0.952 |
| LOC100696013 | nsdhl | ENSONIP00000020011 | ENSONIP00000067574 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. | 0.650 |
| LOC100696013 | sc5d | ENSONIP00000020011 | ENSONIP00000049207 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.835 |
| LOC100696185 | LOC100696013 | ENSONIP00000073431 | ENSONIP00000020011 | Delta7-sterol 5-desaturase. | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. | 0.835 |
| LOC100696185 | LOC100702293 | ENSONIP00000073431 | ENSONIP00000024904 | Delta7-sterol 5-desaturase. | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 0.945 |
| LOC100696185 | LOC100704054 | ENSONIP00000073431 | ENSONIP00000060011 | Delta7-sterol 5-desaturase. | Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4; Belongs to the cytochrome P450 family. | 0.529 |
| LOC100696185 | LOC100709377 | ENSONIP00000073431 | ENSONIP00000041817 | Delta7-sterol 5-desaturase. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.646 |
| LOC100696185 | Sqle | ENSONIP00000073431 | ENSONIP00000000207 | Delta7-sterol 5-desaturase. | Squalene epoxidase a. | 0.856 |