Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
phf2Family with sequence similarity 120A. (1082 aa)    
Predicted Functional Partners:
LOC100693655
Uncharacterized protein.
   
 
 0.644
UPF1
UPF1 RNA helicase and ATPase.
   
 
 0.644
ttll2
Tubulin tyrosine ligase-like family, member 2.
      
 0.577
rbm45
RNA binding motif protein 45.
    
   0.575
eral1
Era-like 12S mitochondrial rRNA chaperone 1.
   
 
 0.540
LOC100709775
Ring finger and CCCH-type domains 2.
    
   0.535
fmr1
Fragile X mental retardation 1.
   
 
 0.525
I3IUB9_ORENI
RBR-type E3 ubiquitin transferase.
      
 0.496
smyd4
SET and MYND domain containing 4.
      
 0.493
I3KR78_ORENI
Sorting nexin 14.
   
   0.490
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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