Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100691312Agouti domain-containing protein. (169 aa)    
Predicted Functional Partners:
LOC100695984
Melanocortin 4 receptor.
    
 0.997
agrp2
Agouti-related protein-like precursor.
  
  
 0.977
LOC100534576
Preproghrelin.
   
  
 0.942
npy
Neuropeptide Y.
      
 0.916
pomc
Uncharacterized protein.
      
 0.899
LOC100708840
Proopiomelanocortin.
      
 0.899
ASIP2
Agouti signaling peptide 2.
  
  
  0.885
lepr
Uncharacterized protein.
    
 
 0.805
NPY
Neuropeptide Y.
      
 0.784
lepa
Leptin A.
      
 0.761
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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