Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100708437VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1216 aa)    
Predicted Functional Partners:
ENSONIP00000034338
Integrin beta 2.
   
 0.957
LOC100703476
Integrin beta.
   
 0.957
cd226
CD226 molecule.
    
 0.927
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
     
 0.917
SRC
Tyrosine-protein kinase.
   
  0.917
LOC100696389
Uncharacterized protein.
     
 0.917
LOC100705099
CRK proto-oncogene, adaptor protein.
     
 0.917
LOC100692677
Tyrosine-protein kinase.
   
  0.917
I3JD82_ORENI
F11 receptor, tandem duplicate 1.
     
 0.917
Bcar1
BCAR1 scaffold protein, Cas family member.
     
  0.916
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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