STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsd11b211-beta hydroxysteroid dehydrogenase type 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (406 aa)    
Predicted Functional Partners:
cyp11b
Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.968
LOC100534568
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
     
 0.937
LOC100703376
Cytochrome P450, family 21, subfamily A, polypeptide 2.
   
 
 0.927
LOC100703009
Hydroxysteroid (11-beta) dehydrogenase 1-like a.
  
 
0.922
LOC100710599
Hydroxysteroid (11-beta) dehydrogenase 1-like a.
  
 
0.922
AKR1D1
Aldo-keto reductase family 1 member D1.
   
 
 0.911
LOC109194203
Aldo_ket_red domain-containing protein.
   
 
 0.911
nr3c2
Nuclear receptor subfamily 3, group C, member 2.
   
 
 0.688
hsd17b3
Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
   
0.610
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
   
  
 0.601
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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