STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cebpaCCAAT/enhancer-binding protein. (295 aa)    
Predicted Functional Partners:
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
    
 0.709
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.709
pparg
Peroxisome proliferator activated receptor gamma.
   
 0.695
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
    
 0.663
spi1
Spi-1 proto-oncogene b.
   
 0.649
e2f1
E2F transcription factor 1.
    
 0.647
LOC102082412
Cyclin-dependent kinase inhibitor 1A.
   
 0.625
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
    
 0.624
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.624
ENSONIP00000042411
Cytochrome c oxidase subunit 5A, mitochondrial.
   
 0.597
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.